Clinical Trial Laboratory Data Nested Within Subject: Components of Variance, Sample Size and Cost

نویسندگان

چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Clinical Trial Laboratory Data Nested With in Subject: Components of Variance, Sample Size and Cost.

Nesting of experimental factors is well established in statistical design literature related to agricultural, environmental and engineering studies. It is perhaps not sufficiently discussed in biological and laboratory experiments stemming from the use of human bio-specimens, where sample size considerations are often provided a priori on subject level, but there is little advice regarding the ...

متن کامل

Power and sample size for nested analysis of molecular variance.

Analysis of molecular variance (AMOVA) is a widely used tool for quantifying the contribution of various levels of population structure to patterns of genetic variation. Implementations of AMOVA use permutation tests to evaluate null hypotheses of no population structure within groups and between groups. With few populations per group, between-group structure might be impossible to detect becau...

متن کامل

Asymptotic algorithm for computing the sample variance of interval data

The problem of the sample variance computation for epistemic inter-val-valued data is, in general, NP-hard. Therefore, known efficient algorithms for computing variance require strong restrictions on admissible intervals like the no-subset property or heavy limitations on the number of possible intersections between intervals. A new asymptotic algorithm for computing the upper bound of the samp...

متن کامل

Optimum Block Size in Separate Block Bootstrap to Estimate the Variance of Sample Mean for Lattice Data

The statistical analysis of spatial data is usually done under Gaussian assumption for the underlying random field model. When this assumption is not satisfied, block bootstrap methods can be used to analyze spatial data. One of the crucial problems in this setting is specifying the block sizes. In this paper, we present asymptotic optimal block size for separate block bootstrap to estimate the...

متن کامل

Presenting Clinical and Laboratory Data of Childhood Acute Lymphoblastic Leukemia

Abstract Background Leukemia is the most prevalent childhood cancer and Acute Lymphoblastic Leukemia (ALL) constitutes 75% of all cases. The most frequent presenting symptoms are fever, weight loss and pallor. Early detection of clinical symptoms positively affects timely diagnosis. The objectives of the present study were to assess frequency of presenting symptoms, laboratory data, immune ph...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Biometrics & Biostatistics International Journal

سال: 2015

ISSN: 2378-315X

DOI: 10.15406/bbij.2015.02.00029